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MT-2 / Melanotan-II
Melanotan-II is a synthetic analogue of alpha-MSH studied for its effects on melanogenesis and related pathways in preclinical research. Supplied as a lyophilized powder for research use only.
Compound information
What is MT-2 / Melanotan-II?
Stability information
Research highlights
Safety & regulatory context: Melanotan-II is not FDA-approved and the literature includes adverse-event case reports; the areas below are strictly research-oriented.
Non-selective melanocortin agonism
Research on activation across MC1R, MC3R, MC4R, and MC5R receptors.
Melanogenesis signaling
Studies examining melanin synthesis via the MC1R pathway.
MC4R-mediated pathways
Investigating central melanocortin-4 receptor signaling and energy balance.
Cyclic peptide stability
Mechanistic work on the cyclic heptapeptide structure and potency.
Sources & references
Safety & regulatory context: Melanotan-II is not FDA-approved. Published case reports associate it with serious adverse events (including melanoma, priapism, rhabdomyolysis, and renal infarction). The human literature is limited to small early-phase studies and case series.
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization
All citations link directly to primary literature. sthrn labs does not reproduce, excerpt, or summarize article content.
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
